LGS Mixed Practice Test #316

Question 1

A prodrug is an inactive compound that is metabolized in the body to an active drug. Which of the following is a common metabolic reaction that converts an ester prodrug into its active form?

Accepted Answer

C. Hydrolysis — Many prodrugs are designed as esters that undergo hydrolysis, typically by esterases found in the liver, plasma, or gastrointestinal tract, to release the active drug (often a carboxylic acid or alcohol). Oxidation and reduction are also common metabolic reactions, but hydrolysis is specific for activating ester prodrugs. Glucuronidation is generally a Phase II detoxification pathway.

Answer

A. Oxidation

Answer

B. Reduction

Answer

D. Glucuronidation

Question 2

Most populous district:‌​‍

Accepted Answer

Malappuram — Malappuram — most populous district (2011 Census).‌​‍

Answer

Ernakulam

Answer

Thiruvananthapuram

Answer

Thrissur

Question 3

The NCERT Class 11 Sociology book 'Understanding Sociology' covers:

Accepted Answer

Sociological theories, methods, institutions (family, education, economy, polity, religion) — Standard intro sociology curriculum — theories, research, and major social institutions.

Answer

Only Indian sociology

Answer

Only statistics

Answer

Only politics

Question 4

Brownian motion refers to:‌​‍

Accepted Answer

Random zigzag motion of colloidal particles in fluid — Observed by Robert Brown (1827); explained by Einstein via molecular collisions.‌​‍

Answer

Rotation of Earth

Answer

Orderly vibration

Answer

Tide movement

Question 5

Niacin (Vitamin B3) plays a vital role in cellular metabolism. Its biologically active forms, NAD+ and NADP+, function primarily as:

Accepted Answer

C. Coenzymes in redox reactions — Niacin, or Vitamin B3, is a precursor to the coenzymes Nicotinamide Adenine Dinucleotide (NAD+) and Nicotinamide Adenine Dinucleide Phosphate (NADP+). These coenzymes are crucial electron carriers in numerous cellular redox reactions, playing central roles in energy metabolism (e.g., glycolysis, oxidative phosphorylation) and biosynthetic pathways.

Answer

A. Structural components of cell membranes

Answer

B. Precursors for neurotransmitters

Answer

D. Regulators of gene expression

Question 6

Arjun is:‌​‍

Accepted Answer

Tank — Main Battle Tank by DRDO.‌​‍

Answer

Missile

Answer

Submarine

Answer

Aircraft

Question 7

Convert 180 km/h to m/s:‌​‍

Accepted Answer

50 m/s — 180 × (5/18) = 50 m/s (shortcut: km/h × 5/18 = m/s).‌​‍

Answer

30 m/s

Answer

45 m/s

Answer

60 m/s

Question 8

The Diwan Sir C.P. Ramaswami Iyer's resignation in 1947 was primarily due to which of the following events?

Accepted Answer

A. The Punnapra-Vayalar uprising against his autocratic rule — Sir C.P. Ramaswami Iyer resigned in 1947 following the violent Punnapra-Vayalar uprising (1946), a communist-led rebellion against his policies. While integration into India (1949) was a later development, the uprising directly triggered his resignation.

Answer

B. The Quit India Movement's impact on Travancore

Answer

C. The integration of Travancore into the Indian Union

Answer

D. The assassination of Mahatma Gandhi

Question 9

Oscar 2024 Best Picture:‌​‍

Accepted Answer

Oppenheimer — Oppenheimer won Best Picture.‌​‍

Answer

Poor Things

Answer

Killers of the Flower Moon

Answer

Barbie

Question 10

The charge on an electron is approximately:‌​‍

Accepted Answer

−1.6 × 10⁻¹⁹ C — Electron carries one unit negative charge = −1.6 × 10⁻¹⁹ coulomb.‌​‍

Answer

−9.1 × 10⁻³¹ C

Answer

0

Answer

+1.6 × 10⁻¹⁹ C

LGS Mixed Practice Test #316