KAS Prelims Mixed Practice Test #473

Question 1

Which of the following statements about chiral drugs is FALSE?

Accepted Answer

B. Enantiomers of a chiral drug always have identical pharmacological activity. — Enantiomers of a chiral drug typically have different pharmacological activities, potencies, and pharmacokinetic profiles because biological systems (receptors, enzymes) are chiral and can selectively interact with one enantiomer over the other. The other statements correctly describe aspects of chirality in drugs.

Answer

A. Chiral drugs contain at least one asymmetric carbon atom.

Answer

C. Stereoisomers have the same molecular formula but different spatial arrangements.

Answer

D. The body can often distinguish between enantiomers, leading to different pharmacokinetic profiles.

Question 2

Which of the following drugs is a selective serotonin reuptake inhibitor (SSRI)?

Accepted Answer

B. Fluoxetine — Fluoxetine is an SSRI used for depression and anxiety disorders. Amitriptyline is a tricyclic antidepressant, diazepam is a benzodiazepine, and haloperidol is an antipsychotic.

Answer

A. Amitriptyline

Answer

C. Diazepam

Answer

D. Haloperidol

Question 3

A postpartum mother at 6 weeks requests contraception. She is breastfeeding exclusively and her menses have not returned. Which of the following is the MOST appropriate contraceptive method for her?

Accepted Answer

B. Progestin-only pill (POP) — The progestin-only pill (POP) is the safest contraceptive choice for a breastfeeding mother, as it does not affect milk production or infant growth. COCP is contraindicated due to estrogen's impact on lactation. Cu-IUD and DMPA are effective but may cause irregular bleeding, making POP preferable in the early postpartum period. Lactational amenorrhea alone is unreliable after 6 weeks postpartum.

Answer

A. Combined oral contraceptive pill (COCP)

Answer

C. Copper intrauterine device (Cu-IUD)

Answer

D. Depot medroxyprogesterone acetate (DMPA) injection

Question 4

Golden rice is genetically engineered to produce:‌​‍

Accepted Answer

β-carotene (provitamin A) in endosperm — Combats Vitamin A deficiency. ‌​‍Genes from daffodil and soil bacterium. Developed by Ingo Potrykus.

Answer

Higher protein

Answer

Resistance to insects

Answer

More yield

Question 5

Rubber #1 state:‌​‍

Accepted Answer

Kerala — Kerala (~90% of India's rubber).‌​‍

Answer

Tripura

Answer

Karnataka

Answer

Tamil Nadu

Question 6

Synonym of PROLIFIC:‌​‍

Accepted Answer

Productive — Producing much.‌​‍

Answer

Slow

Answer

Unproductive

Answer

Limited

Question 7

Kidneys' main function:‌​‍

Accepted Answer

Filtration of blood — Filter waste, form urine.‌​‍

Answer

Digestion

Answer

Pumping blood

Answer

Respiration

Question 8

Which is the highest mountain in Europe?‌​‍

Accepted Answer

Elbrus — Mt. Elbrus (5,642m).

Answer

Mont Blanc

Answer

Matterhorn

Answer

Etna

Question 9

A book giving meanings of words is a:‌​‍

Accepted Answer

Dictionary — Dictionary defines words; thesaurus gives synonyms; encyclopedia gives facts.‌​‍

Answer

Encyclopaedia

Answer

Thesaurus

Answer

Atlas

Question 10

Kerala's first woman DIG (police):‌​‍

Accepted Answer

R Sreelekha — R Sreelekha.‌​‍

Answer

B Sandhya

Answer

Lakshmi

Answer

Both A and B served

KAS Prelims Mixed Practice Test #473