Plus 2 Lecturer Mixed Practice Test #1061

Question 1

What is the primary mechanism of action of statins (HMG-CoA reductase inhibitors) in lowering cholesterol?

Accepted Answer

C. Reducing cholesterol synthesis in the liver by inhibiting a key enzyme. — Statins work by competitively inhibiting HMG-CoA reductase, a crucial enzyme in the mevalonate pathway responsible for endogenous cholesterol synthesis in the liver. This reduction in hepatic cholesterol synthesis leads to an upregulation of LDL receptors on hepatocytes, increasing the clearance of LDL from the blood. Other options describe mechanisms of different lipid-lowering drugs.

Answer

A. Increasing the excretion of bile acids.

Answer

B. Inhibiting the absorption of dietary cholesterol from the intestine.

Answer

D. Enhancing the activity of lipoprotein lipase.

Question 2

Arundhati Roy's Booker winner (1997):

Accepted Answer

The God of Small Things — Set in Kerala's Ayemenem. Explores caste, forbidden love, family. Also notable for her political essays.

Answer

Beloved

Answer

Midnight's Children

Answer

A Fine Balance

Question 3

Malaria caused by:

Accepted Answer

Plasmodium (protozoa) — Plasmodium parasite, transmitted by female Anopheles mosquito.

Answer

Virus

Answer

Bacteria

Answer

Fungus

Question 4

The basic structural and functional unit of life is:‌​‍

Accepted Answer

Cell — Cells are the smallest units of life; discovered by Robert Hooke (1665).‌​‍

Answer

Organelle

Answer

Tissue

Answer

Organ

Question 5

The synonym of 'EXTRICATE' is:‌​‍

Accepted Answer

Free — Extricate means to free or release from a difficult situation. ‌​‍Its antonym would be 'entangle' or 'complicate'.

Answer

Complicate

Answer

Tie

Answer

Entangle

Question 6

Sabarimala review pending before:‌​‍

Accepted Answer

9-judge — Referred to 9-judge bench.‌​‍

Answer

11-judge

Answer

5-judge

Answer

7-judge

Question 7

K.R. Meera:‌​‍

Accepted Answer

Novelist (Aarachar) — Contemporary novelist.‌​‍

Answer

Politician

Answer

Musician

Answer

Actor

Question 8

Kerala's unique physiography significantly influences its river systems. Which of the following geographical features is the primary reason for the short length, high velocity, and predominantly west-flowing nature of most rivers in the state?

Accepted Answer

B. The steep gradient of the Western Ghats on its western face, close to the Arabian Sea. — The Western Ghats rise abruptly and very close to the Arabian Sea on Kerala's western side. This steep and short slope causes rivers originating in the Ghats to flow rapidly over a short distance directly into the sea, thus making them short, swift, and predominantly west-flowing. While rainfall contributes to water volume and forests/soil influence runoff, the fundamental short and swift nature is due to the steep physiographic drop.

Answer

A. The extensive network of backwaters and estuaries along the coastal plains.

Answer

C. The high annual rainfall concentrated during the southwest monsoon season.

Answer

D. The prevalence of laterite soil and dense tropical evergreen forests in the midlands.

Question 9

Cellulose is polymer of:

Accepted Answer

β-glucose (β-1,4 linkages) — Straight chains, hydrogen bonded. Humans lack cellulase — can't digest. Ruminants and termites have symbiotic microbes.

Answer

α-glucose

Answer

Fructose

Answer

Mannose

Question 10

Synonym of AMICABLE:‌​‍

Accepted Answer

Friendly — Friendly.‌​‍

Answer

Cold

Answer

Strange

Answer

Hostile

Plus 2 Lecturer Mixed Practice Test #1061